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24th February 2010: Day One
09.15 - 09.30 Welcome and Introduction
Richard Moore, Institute of Nanotechnology, UK
Keynote Presentation
09.30 - 10.10 Multifunctional Pharmaceutical Nanocarriers for Delivery of Drugs, Genes and Diagnostics Professor Vladimir Torchilin, NorthEastern University, USA
10.10 - 10.55 Roadmaps in Nanomedicine towards 2020 Sebastian Lange, Nanomedicine ETP
11.00 - 11.25 Refreshments
Session 1: Nanoscale Drug Delivery / Drug Design Chair: Richard Moore, Institute of Nanotechnology, UK
11.30 - 11.55 Challenges to the Development of Nanomedicines Dr Simon Holland, Director, Process Understanding and Control Pharmaceutical Development MOST, GlaxoSmithKline, UK
  • Drivers for nanomedicines
  • Current portfolio of nanomedicines
  • Technological, environmental and ethical barriers to product development
12.00 - 12.25 Novel Non-Attrition Approaches to Water-Based Formulation of Poorly Soluble APIs Professor Steve Rannard, Chief Scientific Officer, IOTA NanoSolutions, UK
  • New non-attrition nanoparticle formation approaches will be described
  • Results from in vivo testing of anti-infectives from IV and Oral formulations will be discussed
  • Enhanced activity and bioavailability will be demonstrated through several case studies
12.30 - 12.55 Nanomedicines for the Delivery of Drugs and Genes Professor Ijeoma Uchegbu, University College London, UK
13.00 - 13.55 Lunch
14.00 - 14.25 Nanotechnology in CNS Drug Discovery Dr Mo Alavijeh, Pharmidex Ltd, UK
14.30 - 14.55 EC-facilitated Development of Targeted Nanomedicines Professor Gert Storm, University of Utrecht, The Netherlands
  • targeted nanomedicines
  • chronic inflammatory disease and cancer
  • sponsoring by the European Commission (FP6)
15.00 - 15.25 Nanotechnologies for Nucleic Acid Delivery Professor Elias Fattal, Université Paris-Sud, France
15.30 - 15.55 Refreshments
Session 2: Disease Imaging and Treatment Chair: Professor dr. Vinod Subramaniam, University of Twente, The Netherlands
16.00 - 16.25 NanoMedicine: Converging Medical Technologies Impacting Healthcare Professor Hans Hofstraat, Philips Healthcare, The Netherlands
  • Nanotechnology
  • Convergence of Medical Technologies and Biotechnology
  • Diagnostics for early identification of disease and stratification of patients
  • Local and image-guided drug delivery
  • Electronic pills
  • Regenerative medicine
16.30 - 16.55 3D Visualization of Fluorescence Distribution Dr Jeroen van den Wijngaard, Academic Medical Center Amsterdam, The Netherlands
17.00 - 17.25 Towards Optoacoustic Molecular Imaging Using Targeted Particle Systems Dr Robert Lemor, Fraunhofer Institute for Biomedical Engineering, Germany
  • Multiscale Optoacoustic Imaging & Contrast Agent technology
  • Cytotoxicity of metallic and resorbable particle systems
17.30 Close of Day One
17.30 - 18.30 Poster Session and Drinks Reception
25th February 2010: Day Two
09.30 - 09.35 Welcome and Introduction to Day Two
Professor Tony Turner, Cranfield University, UK
Session 3: Nanotechnology in Diagnostics and Monitoring Chair: Professor Tony Turner, Cranfield University, UK
09.35 - 10.00 'Pocket Pathology' –using nanotechnology to turn the vision into reality Elaine Warburton, QuantuMDx Group, UK
  • The clinical and economic drive for globally affordable diagnostics
  • ‘Pocket pathology’ – using nanotechnology to realise personalised medicine
  • Using nanowire biosensors for diagnostic and DNA sequencing applications
10.05 - 10.30 DNA Diversity and Personalized Medicine Professor Urs Meyer, University of Basel BioZentrum, Switzerland
  • The interindividual variation of the human genome sequence explains differences in drug response and is an important component of personalized medicine
  • Personalized medicine is a strategy to improve clinical outcome by precise diagnosis and by optimizing drug choice and drug dose to the need of the individual patient
  • Personalized medicine is a strategy to improve clinical outcome by precise diagnosis and by optimizing drug choice and drug dose to the need of the individual patient
10.35 - 11.00 Refreshments
11.05 - 11.30 Advancing Microbiology with Miniaturized Culture Chips Fabricated from Nanoporous Aluminium Oxide Dr Colin Ingham, Microdish BV, The Netherlands
  • The fabrication and properties of highly subdivided culture chips based around porous aluminium oxide
  • The application of culture chips in microbial diagnostics and screening
  • Printing and handling microorganisms on this format
11.35 - 12.00 Nanomedicine Enabling Point of Care Diagnostics Applications Dr Paul Galvin, Tyndall National Institute, Ireland
  • Examples of some diagnostic solutions based on nanomedicine will be discussed, which are enabling target biomolecules to be captured, concentrated and detected within low cost automated microsystems
  • The challenges for enabling the accuracy and reproducibility of the test, together with an appropriate cost model will be discussed
  • Potential ethical issues will be highlighted
  • Potential commercialisation issues will also be addressed
12.05 - 12.30 Nanosensors for Superbugs and Superdrugs Dr Rachel McKendry, University College London, UK
12.35 - 13.30 Lunch
Session 4: Regenerative Medicince Chair: Professor dr. George Robillard, Biomade Technology Foundation, The Netherlands
13.35 - 14.00 Novel Approaches to Whole Organ Tissue Engineering Dr Paolo Macchiniarini, Head of Thoracic Surgery, Barcelona University Hospital Clinic, Spain
14.05 - 14.30 Bio-inspired Nanomaterials for Regenerative Medicine and Biosensing Professor Molly Stevens, Imperial College London
14.35 - 15.00 The Intersection of Nanotechnology and Healthcare Dr Rutledge Ellis-Behnke, Massachusetts Institute of Technology, USA and University of Hong Kong, China
  • Using nanotechnology to repair the brain
  • Using nanotechnology to stop bleeding in less than 15 seconds
15.05 - 15.30 Refreshments
15.35 - 16.00 Nanofibrous Scaffolds for Soft Tissue Repair Dr Mike Raxworthy, Neotherix Ltd, UK
16.05 - 16.30 Nanotechnology Application to the Nervous System: Carbon Nanotubes and Brain Signaling Dr Laura Ballerini, University of Trieste, Italy
  • Nanomaterials enter the realm of basic biological functional units due to their ability to functional integrate with bio-systems
  • In recent years we reached an increased interest and improved understanding of such interactions with biological systems at a subcellular level
  • A large body of research is emerging that hints at the potential applications of nanotechnology in neurosciences, although the basic scientific and clinical progress is limited by the intrinsic complexities of dealing with the mammalian central nervous system
  • May neurons change their behavior by interacting with interfaces at the nanoscale?
  • Can these interactions affect neuronal performance?
  • Have these interactions the potential to improve neuroelectronic hybrids and neuronal network behavior?
16.35 - 16.45 Close of Conference

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