Nanoparticles Hunt Down Cancer Cells

 
Post new topic   Reply to topic    Institute of Nanotechnology Forum Index -> Nanobiomed
View previous topic :: View next topic  
Author Message
nanoorg
Site Admin


Joined: 16 Mar 2004
Posts: 1392

PostPosted: Mon Aug 24, 2009 3:47 pm    Post subject: Nanoparticles Hunt Down Cancer Cells Reply with quote

Cancer cells can be detected then destroyed using a nanostructure designed by South Korean researchers.

Bong Hyun Chung and colleagues at the Korea Research Institute of Bioscience and Biotechnology in Daejeon base their structures on hollow gold nanoparticles.


The modified gold nanoparticles seek out and destroy cancer cells

The structures have antibodies on their surface which allow them to bind to cancer cells. They also contain gadolinium, which acts as a molecular resonance imaging (MRI) contrast agent and allows the cells to be seen. When Chung shone an infrared laser on the gold nanoparticles, the heat that formed destroyed the surrounding cancer cells.

The gold nanostructures overcome the drawbacks of commonly-used iron oxide MRI contrast agents, suggests Chung. Iron can lead to interference and negative contrast effects, causing errors in diagnosis. The design of the gold nanostructures leads to an enhanced signal and better diagnosis, he says.

Chung's approach is non-invasive and is likely to be effective in the treatment of early-stage cancers because it treats a specific area, unlike chemotherapy which affects the whole body. In the future 'the nanoparticles may be used for the analysis of cancer dissection in surgery', says Chung.

Link to journal article:
Paramagnetic gold nanostructures for dual modal bioimaging and phototherapy of cancer cells

Yong Taik Lim, Mi Young Cho, Bang Sil Choi, Jung Min Lee and Bong Hyun Chung, Chem. Commun., 2008 DOI: 10.1039/b810240f

Source: http://www.rsc.org/Publishing/ChemTech/Volume/2008/10/combined_cancer_treatment.asp
Back to top
View user's profile Send private message
Display posts from previous:   
Post new topic   Reply to topic    Institute of Nanotechnology Forum Index -> Nanobiomed All times are GMT
Page 1 of 1
 

 
Jump to:  
You cannot post new topics in this forum
You cannot reply to topics in this forum
You cannot edit your posts in this forum
You cannot delete your posts in this forum
You cannot vote in polls in this forum


Powered by phpBB © 2001, 2002 phpBB Group