Nano Test for Heart Attacks - protein detection

 
Post new topic   Reply to topic    Institute of Nanotechnology Forum Index -> Nanobiomed
View previous topic :: View next topic  
Author Message
nanoorg
Site Admin


Joined: 16 Mar 2004
Posts: 1392

PostPosted: Wed Sep 20, 2006 11:17 am    Post subject: Nano Test for Heart Attacks - protein detection Reply with quote

Nano Test for Heart Attacks - Improved Protein Detection is Key
by Kevin Bullis

Every year, thousands of heart attack victims are sent home without treatment by emergency-room doctors because tests don't show clear signs of a problem, such as elevated levels of proteins released into the blood by dying heart cells. But an ultrasensitive detector, expected to be widely available for clinical evaluation later this year, could save lives by recognizing those proteins at a thousandth the concentration that current methods can detect -- or even less.

The device, built by Nanosphere of Northbrook, IL, is based on research by Northwestern University chemist Chad Mirkin, who developed a way to coat gold nanoparticles with selectively "sticky" substances, such as DNA strands constructed to bind with complementary target DNA in a sample. When the nano-particles, stuck to their targets, attach to a microarray that also bears complementary DNA, a digital camera can scan them to find the sample's DNA concentration. A similar method, using antibodies as the glue, can measure protein concentrations.

Clinical trials are now testing techniques that could be used to diagnose previously undetected heart disease and Alzheimer's disease. Nanosphere's CEO, Bill Moffitt, says the device could reveal levels of telltale Alzheimer's proteins in the blood at concentrations "undetectable by any other technology."


Source:

http://www.technologyreview.com/


This story was first posted on 11th July 2006.
Back to top
View user's profile Send private message
Display posts from previous:   
Post new topic   Reply to topic    Institute of Nanotechnology Forum Index -> Nanobiomed All times are GMT
Page 1 of 1
 

 
Jump to:  
You cannot post new topics in this forum
You cannot reply to topics in this forum
You cannot edit your posts in this forum
You cannot delete your posts in this forum
You cannot vote in polls in this forum


Powered by phpBB © 2001, 2002 phpBB Group