Nano Blood-stopper Starts Clinical Trials

 
Post new topic   Reply to topic    Institute of Nanotechnology Forum Index -> Nanobiomed
View previous topic :: View next topic  
Author Message
nanoorg
Site Admin


Joined: 16 Mar 2004
Posts: 1392

PostPosted: Fri May 08, 2009 9:31 am    Post subject: Nano Blood-stopper Starts Clinical Trials Reply with quote

A startup based in Cambridge, MA, says that it plans to soon begin clinical trials of a nanostructured material that stops bleeding almost instantly. A startup called Arch Therapeutics has licensed the technology from MIT and is developing manufacturing processes for making it in large amounts.

The new material can be poured over a site and will stop the bleeding almost at once.


Blood stopper: The clear fluid in this dish transforms into a gel in the presence of blood; such a gel can stops bleeding almost instantly. Credit: Asia Kepka


The first application, pending Food and Drug Administration approval, will be for use during surgery to quickly stop bleeding and even prevent it in the first place. Floyd Loop, currently an advisor to Arch Therapeutics, and formerly a cardiovascular surgeon and the head of Cleveland Clinic, says that it could be useful in a wide variety of surgeries, including brain, heart, and prostate. For example, he says that when large tumors are removed, "there's a lot of diffuse bleeding around the site, and you have to spend a lot of time with sponges and cautery stopping it."

Loops says that in addition to saving time, which can improve the outcome of a surgery, the material could decrease the need for transfusions and reoperations to control bleeding. What's more, it could reduce the risk of infection. It could be used, for instance, to prevent leakage after bowel-repair surgery. "I've never seen anything like it," Loop says.

Eventually, the material could be used by first responders to stop bleeding at accident sites and on the battlefield. It has a long shelf life, which makes it attractive for use in first-aid kits. It's also easily broken down by the body, so it doesn't have to be removed, unlike other agents for stopping blood flow. However, Loop cautions that further tests are needed to confirm that the material will work in nonsurgical applications.

The material, a synthetic peptide, was discovered at MIT in the early 1990s. But it wasn't until a few years ago that its potential for stopping bleeding was discovered. Rutledge Ellis-Behnke , a researcher at MIT's Department of Brain and Cognitive Sciences, was exploring its potential use to promote the healing of brain injuries. When he applied a liquid containing the synthetic peptides to a wound site in animal experiments, bleeding in the area stopped within a few seconds. Arch Therapeutics was founded in mid-2006 to develop the material for commercial use. The company made its first public appearance late last month when it announced a finalized licensing agreement for the new technology.


Source: http://www.technologyreview.com/Nanotech/20755/
Back to top
View user's profile Send private message
Display posts from previous:   
Post new topic   Reply to topic    Institute of Nanotechnology Forum Index -> Nanobiomed All times are GMT
Page 1 of 1
 

 
Jump to:  
You cannot post new topics in this forum
You cannot reply to topics in this forum
You cannot edit your posts in this forum
You cannot delete your posts in this forum
You cannot vote in polls in this forum


Powered by phpBB © 2001, 2002 phpBB Group