New Stable Polymer Nanotube May Have Future in Biotech

 
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PostPosted: Tue Feb 14, 2006 5:15 pm    Post subject: New Stable Polymer Nanotube May Have Future in Biotech Reply with quote

NIST Researchers Say that New Type of Stable Polymer Nanotubes May Have a Future in Biotechnology

Scientists at the National Institute of Standards and Technology (NIST) have created polymer nanotubes that are unusually long (about 1 centimeter) as well as stable enough to maintain their shape indefinitely. Described in a new paper in Proceedings of the National Academy of Sciences,* the NIST nanotubes may have biotechnology applications as channels for tiny volumes of chemicals in nanofluidic reactor devices, for example, or as the “world’s smallest hypodermic needles” for injecting molecules one at a time.

Carbon nanotubes are of keen interest in nanotechnology research, especially for making ultrastrong fibers and other structures. Nanotubes made from other materials are used for transport in biochemical applications, but are typically fragile and usually collapse within a few hours. The NIST team developed processes for extending the shelf life of polymer nanotubes—considered essential for commercial applications—and forming sturdy nanotube network structures.

First the researchers made tiny, fluid-filled spherical containers with bi-layer membranes consisting of polymers with one end that likes water and one end that does not. (These fluid-filled containers are a spin-off of liposomes, artificial cells with fatty membranes used in cosmetics and for drug delivery.) The researchers made the membranes stretchy by adding a soap-like fluid to change the polymer membranes’ mechanical properties. Then they used “optical tweezers” (highly focused infrared lasers) or tiny droppers called micropipettes to pull on the elastic membranes to form long, double-walled tubes that are less than 100 nanometers in diameter. (View a movie of this process.)

A chemical was added to break bonds between atoms in one section of the polymers and induce new bonds to form between the two different sections, forming a rigid “cross-linked” membrane. The nanotubes are then snipped free from the parent cell with an “optical scalpel” (highly focused ultraviolet laser pulse). The nanotubes maintain their shape even after several weeks of storage, and can be removed from the liquid solution and placed on a dry surface or in a different container. The optical tweezers can be used to custom build nanotube network structures. The work was supported in part by the Office of Naval Research.

Source: National Institute of Standards and Technology (NIST).

URL: http://www.nist.gov

This story was posted on 6 February 2006.
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